UNT GCA will continue to use the S2S feature with the introduction of GRAMS. This will allow continued functionality of linking the 424 application with the internal Funding Proposal for Grants.Gov submissions. GRAMS offers some additional features between the Funding Proposal and the 424 application, as discussed below.
As a Principal Investigator (PI), you will learn:
This section identifies funding proposal fields that will map to the SF424. It explains how they map, and any other important considerations for that field when creating a S2S application.
Please note that this section is not a comprehensive list of ALL fields, but only those that impact the SF424. For information on completing other funding proposal fields, refer to the Funding Proposal Guide.
The General Proposal Information SmartForm includes basic information about the proposal that will map to the SF424 application on the SF424 R&R cover page and R&R Senior/Key Person Profile.
General Proposal Information - SmartForm Page |
Field |
SF424 Mapping |
Notes |
1. Type of application |
Type of Application on the SF424 R&R Cover page. Can be updated on the SF424 if needed. |
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3. Long title of proposal |
Descriptive Title of Applicant’s Project on the SF424 R&R Cover Page. |
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4. Program Director/Principal Investigator/Project Lead/Fellow |
PI on SF424 application, including R&R cover page and R&R Senior/Key Person Profile. |
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5. Direct sponsor |
Select the direct sponsor and it will show on the R&R Cover Page. |
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8. Expected Start Date |
Proposed Project Start Date on the SF424 R&R Cover Page. |
The Personnel page includes information about internal project personnel. Senior/Key personnel or other significant contributors listed on this page will map to the R&R Senior/Key Personnel Form.
Personnel - SmartForm Page |
Field |
SF424 Mapping |
Notes |
1. Program Director/Principal Investigator/Project Lead/Fellow |
PI on SF424 application, including R&R Senior/Key Person Profile.. |
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1b. Biosketch |
Maps to Biosketch for the PI on the R&R Senior/Key Person Profile. |
Biosketches should be uploaded for S2S proposals if required at time of submission. |
1c. Other Support |
Maps to Current & Pending Support for the PI on the R&R Senior/Key Person Profile. |
Current & Pending support should be uploaded for S2S proposals if required at time of submission. |
2. Responsible Department |
Maps to Department on SF424 R&R Cover page and on the R&R Senior/Key Person Profile for the PI. |
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3. Project Personnel |
All personnel in 3a or 3b that are marked as Senior Key Personnel or Other Significant Contributor will map to the R&R Senior/Key Person Profile. People marked as “Other Personnel” will not map to the SF424. |
Proposed Project Start Date on the SF424 R&R Cover Page. |
3a. Institutional Personnel |
Name, Project Role, Biosketch, Current & Pending, and Key designation will map to the R&R Senior/Key Person Profile. |
When internal personnel are selected, information from their Contact Profile in the system will also map to Senior/Key Person Profile-including their position, title, dept, contact information and, for NIH applications, their ERA Commons ID may populate. |
3b. Non-institutional personnel |
Information provided will be mapped to the R&R Senior/Key Personnel Profile such as Prefix, Name, Position/Title, Organization, Department, Division, Street Address, contact information, Credentials, Project Role, Key designation, Biosketch, and Current & Pending. |
This information is only recommended to be entered for S2S submissions so it can map to the 424. Entering for non S2S proposals is not needed. |
Your GCA Specialist will complete this section of the Funding Proposal SmartForm based on the selection in your GCS Request and note this is a S2S which will allow the opportunity number to be found, selected, and linked to your 424 application.
The Budget Periods and Key Dates page contains information about the project start and end dates which will map to the R&R Cover page. Decisions on this field also inform how the funding proposal budget is created. The budget can also map to the SF424 application if desired.
Budget Periods and Key Dates – SmartForm Page |
Field |
SF424 Mapping |
Notes |
3. Date Project Starts |
Proposed Project Start Date on the SF424 R&R Cover Page. |
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4. Date Project Ends |
Proposed Project End Date on the SF424 R&R Cover Page. |
The Compliance Review SmartForm page contains compliance related questions regarding human subjects, animals, and stem cells that will map to the SF424 application.
Compliance Review – SmartForm Page |
Field |
SF424 Mapping |
Notes |
1. Human subjects involved in this project? |
Maps yes or no to human subjects question on the R&R Other Project Information page. |
Note that UNT’s human subject assurances number should automatically default on the R&R Other Project Information page if this is yes. |
1b. IRB review status of this research? |
Based on the selection, the corresponding information will map to the 424. |
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1C. IRB Protocols |
If all protocols listed have an Exemption # listed, the project will be marked as exempt from federal regulations. All applicable exemption numbers will map. If some protocols are exempt but not all, it will map as not exempt. If any protocol is listed as Pending, it will map that the IRB Review is Pending. If all protocols listed are marked as approved, it will map that the IRB review is not pending. If all protocols are listed are approved (none are pending), the IRB approval date will be listed as the most recent protocol approval date. |
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2. Laboratory Animals involved in this project? |
Maps yes or no to vertebrate animals question on the R&R Other Project Information page. |
Note that UNT’s animal welfare assurance number should automatically defaulton the R&R Other Project Information page if this is yes. |
2a. IACUC Protocol Submitted? |
If no is selected, the IACUC review will be marked as pending on the R&R Other Project Information page. If yes is selected, protocol information from 2B will be used for mapping. |
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2b. IACUC Protocols |
If any protocols listed are Pending, it will map that the IACUC Review is Pending. If all protocols listed are marked as approved, it will map that the IACUC review is not pending. If all IACUC protocols listed are approved (none are pending), the IACUC approval date will be listed on the form as the most recent protocol approval date. |
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7. Human Embryonic Stem Cells involved in this project? |
Maps yes or no to PHS 398 Cover Letter Supplement. If yes, and a stem cell line is listed it maps as well. Otherwise, the “stem cell cannot be referenced at this time” box will be checked. |
The Additional Proposal Information SmartForm page includes application institution information and program income information that will map to the SF424.
Additional Proposal Information – SmartForm Page |
Field |
SF424 Mapping |
Notes |
1. Application Institution |
Makes University of North Texas the applicant institution on the SF424 R&R Cover Page and the Project/Performance Site Primary Location on the Project/Performance Site Locations form. |
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2. Program Income |
Maps to the SF424 R&R Cover Page estimated project funding and the PHS 398 Cover Page Supplement. |
This section describes how to develop budgets for S2S submissions. It explains how budgets map and additional special considerations. Please note that the Budgets Guide may also serve as helpful resource for budget development.
The SF424 can use either the R&R Budget form or the PHS 398 Modular Budget form. Modular Budget is only used by the NIH. If this is an NIH modular budget, it’s important to confirm the Budget Period and Project Dates of the funding proposal SmartForm and that yes is selected for the Modular Budget Question. This will ensure your Total Direct Costs, Total Indirect Costs, and Total Project costs are calculated correctly using the modular method. It is also important to note that budget periods and their dates are also determined on the Budget Periods and Key Dates page. This page will be used in accordance with the budget information below when the SF424 budget is created.
When the funding proposal is created, the system automatically creates a project budget with the name of the primary sponsor. This budget should be completed as part of the proposal development process.
Multiple project budgets may be created using the Create Additional Budget activities for various scenarios as discussed in the Budget Guide. If multiple project budgets are created (and marked as include in Consolidate Budgets = Yes), they will all map to the SF424 budget forms with their appropriate rates and values applied.
Note if additional budgets are created as “drafts” to test various scenarios (e.g., budgeting 2 grad students versus3), it’s important to ensure the draft budget is marked as In Consolidated Budgets = No so those drafts do not map to the SF424.
All UNT personnel included in the budget will be listed on the Personnel Cost Definition page and then budgeted on the Personnel Cost page using their % annualized effort, % salary requested, benefits rate, and base salary.
For R&R budgets, each person’s name, role, base salary, effort months, requested salary, and fringe benefits will map to the R&R Budget – Sections A Senior/Key Personnel or to Section B Other Personnel. For other personnel (such as grad students or post docs), the number of individuals listed on the budget will map.
For modular budgets, direct costs map to the PHS 398 Modular budget forms by period and the PHS 398 Modular Budget- Cumulative.
On the Personnel Costs page, personnel can still be budgeted using the standard method described in-depth in the Budget Guide. The below information will give you the standard process and key considerations to keep in mind for S2S applications.
Reminder: Effort is budgeted based on the personnel’s annualized salary and their annual effort percentage in the Funding Proposal.
Therefore, it maps to the R&R budget in the calendar month column. This will need to be manually updated to show the breakout of the academic and summer months.
The general cost types selected and their per period values will map to the R&R Budget by period and the R&R Budget-Cumulative. General cost types will map to the proper section of the form based on either type.
For modular budgets, the general cost types and their per period values will map to the PHS 398 Modular budget forms by period and the PHS 398 Modular Budget- Cumulative. All direct costs (including general cost types and personnel costs) are summed in Box A for each period of the form.
The Budget Justification must be uploaded directly to the SF424 instead of the Attachment page of the budget SmartForm. The document can be uploaded on the R&R Budget – Period 1 – Section L or PHS-398 Modular Budget – Cumulative section.
The document will not map from the project Budget SmartForm to the SF424, so if it is uploaded here it will still need to be uploaded again directly on the SF424 as required.
The following section outlines how to review the 424 Workspace in GRAMS, review the application forms, make updates, and validate.
Typically, your GCA Specialist will have already created your 424 application for you, in response to your GCS request. The SF424 application has its own workspace, similar to how a funding proposal or budget has a workspace. You can navigate to the SF424 workspace by clicking the SF424 link on the funding proposal workspace as shown below. The SF424 workspace displays the proposal title and the SF424 ID. You do not need to remember the SF424 ID, since you can always navigate to the SF424 from the Funding Proposal.
You can follow the breadcrumbs to navigate back to the Funding Proposal.
Below that are the workspace tabs. The History tab shows all activities that are run on the SF424 workspace. The Change Log tab shows when changes are made to the SF424 application SmartForm. If you click on a change and then “View More Details”, it will show you which field was updated.
On the left side of the workspace, you can see the state of the SF424 application. The SF424 will always begin in PreSubmission State. You can use the Edit Grant Application button to open the SF424 SmartForm. When the application is in a read-only state, this button is labeled as “View Grant Application”.
Below these buttons, you will see the SF424 workspace activities.
Because certain information from the Funding Proposal maps to the linked 424 application, it is recommended to complete the funding proposal application first. Once proposal and budget information has been completed in the funding proposal, you are ready to update the 424 to take advantage of this feature. Even though it is recommended to complete the funding proposal first, do not route until the 424 application is ready for review.
From the funding proposal workspace, click the Create-Update SF424 activity.
In Create-Update SF424 window, select the SF424 forms you want to map data to from the Funding Proposal or Budget and Click OK.
Required forms will default to “checked.” Any optional forms can be checked as well. If this proposal includes a budget, either the R&R Budget or PHS 398 Modular Budget form for NIH submissions should be selected.
The status column will update as each form is generated. A success alert appears when the SF424 application has been generated and is ready for review. The window will automatically close once the process is complete; do not “x” out of the window prematurely.
The SF424 has been updated and the information from the Funding Proposal that can map to the 424 should have mapped successfully.
The SF424 should be updated using the Create-Update SF424 activity when future changes are required to the SF424 based on information that came from the Funding Proposal or Budget SmartForm.
Changes to information that was NOT auto populated or mapped by the system may be made directly to the SF424, as there is nowhere to update this information on the Funding Proposal or Budget. Examples include the Research Strategy and other documents. The manual entry fields or documents will not be overwritten by running the CreateUpdate SF424 activity.
However, when SF424 updates are needed for information that was initially entered on the Funding Proposal or Budget SmartForms, then the information should be updated on the Funding Proposal SmartForm first, and then the Create-Update SF424 activity should be run. It is important to note that any change you made to any field on the SF424 which was mapped from the Funding Proposal SmartForms or Budget will be overridden when you execute the Create-Update SF424 activity unless you uncheck that form in the Create-Update SF424 activity. For example, if you updated the person months in the RR budget to show a breakout of academic and summer versus the default, calendar, this will be overridden if running the Create-Update SF424 feature.
It is very important to follow this process for a few reasons:
e.g., If I update my equipment budget from $50,000 to $30,000 directly on the SF424, but not on the budget, then when I run the Create-Update activity again for that form my budget will revert to $50,000.
The same steps are followed as above, but please note, you can select which forms you would like to update. You can unselect any which you would not like to update. You can also add additional forms if something was previously missed.
Note that to select all forms, select the checkbox next to “Action.” You can double click this checkbox to “unselect” all forms.
In the example below, the user is updating the subaward budget as well as the optional PHS 398 Request Form. *Please review the GRAMS Budget Guide for details of Importing Subawards into the SF424 proposal.
The status column will update as each form is processed and will show which forms were “skipped” because they were not selected. A success alert appears when the process is complete, and the window will automatically close; do not “x” out of the window before the process completes.
Once the updates have been made, return to the SF424 workspace to continue the review and completion of the application.
The SF424 application is populated with information from the funding proposal SmartForms, budget SmartForms, and institutional UNT defaults. Additional questions must be answered directly on the SF424 and your documents should be uploaded directly to the SF424 application.
You can review and update your SF424 application information within the SmartForm pages. You can also generate a PDF version of the application from the workspace.
As you review and update the SF424, it is important to consider what kind of updates you are making and where the appropriate place is to make that edit:
This is not a comprehensive guide to completing the SF424 Application as the instructions and required forms may vary based on the Funding Opportunity. When in doubt, always refer to sponsor guidance or reach out to your GCA Specialist with questions. The information below will introduce commonly required forms and how they are populated by the system.
Select Optional Forms Page
SF424 R&R Cover Page
Project/Performance Site Locations
R&R Other Project Information
R&R Senior/Key Person Profile
PHS 398 Cover Page Supplement
PHS398 Research Plan HS398 Research
PHS Human Subjects and Clinical Trials Information
R&R Budget
PHS 398 Modular Budget
R&R Subaward Budget
As you review the SF424 forms, use the validate button to check for errors and ensure you have all required information. Click the Validate button in the top left corner.
The system will detect errors and alert you of them. The red stop sign icon means this issue must be resolved before submitting. Messages with a Yellow Triangle are warnings. Warnings will not stop the submission but should be reviewed to ensure the information is correct. The green checkmark icon means that the information on the page passes validation.
To jump to a message for review, click the link in blue text. You will be brought directly to the field with an error.
Fields with a red asterisk are mandatory. In certain cases, Grants.gov may require additional fields to be completed in addition to the ones required by the system. Validating your application will let you know if any of the required fields have been missed. Always refer to your funding announcement as well for required fields and information.
Please note GRAMS uses both NIH global/local Grants.Gov validations and the NIH web service for validations. Therefore, initial errors/warnings will appear from the local Grants.gov and NIH global validations and once those are corrected, additional errors/and warnings will appear from the NIH web service. Please keep this in mind as once all initial errors/warnings are cleared, you will need to re-run validations as you work to complete your SF424 application.
To upload files, select upload:
A window will pop up allowing you to select a file from our computer. Note, if you do not provide a title, the file name will be used.
After selecting okay, the file is now attached.
Please note, more than one person can be working in the SF424 application at one time. If someone is currently working on a form that you select, you will see the below message and the system will let you know who is also in this form. Updates can still be made, and the form can still be saved.
Once the 424 application is error free and complete, please route the funding proposal for department review. During department and the subsequent Specialist Review, you will not be able to make changes to the Funding Proposal or Budget smartForm unless clarifications or changes are requested. However, you will still have the ability to edit the 424 application. Please keep this is mind any changes you make in the 424 application during this time. For instance, the SF424 application budget should only be updated when in Clarification Requested status so the change can first be made in the Budget SmartForm.
Once the application is ready for submission (all approvals have been obtained and your GCA Specialist has reviewed your proposal) you will validate the submission to confirm the application is ready for submission to Grants.Gov.
After the SF424 has been thoroughly reviewed and is considered complete, validate the submission from the SF424 workspace.
Validating the submission will cause the SF424 to be locked from future editing once any errors have been resolved. Do not validate the submission until your finalized documents have been uploaded. Validating the submission will cause the SF424 to be in “Valid for Submission” State.
On the SF424 workspace, click the Validate Submission Activity. This will run validation with built in sponsor rules (such as NIH) to ensure all required information appears for submission.
A new window will display an error or warning messages. Messages with a red circle icon indicate the issue must be resolved before submission. The yellow triangle icon indicates a warning message. Warnings should be reviewed prior to submission, but the application can be submitted with warnings.
Once all issues are resolved and only warnings that have been vetted to be okay, appear you can click Continue. If you have any questions about the errors or warnings that appear on this page, please cancel, and contact your GCA specialist. Please also notify them of warnings that appeared and that you are comfortable moving forward with as is. If there are no issues, you will automatically be brought to the Validate Submission page.
Note: In the above example, the correct forms have been verified that these were used so it is okay to move forward with submission.
Verify the correct required and optional forms are selected.
Note: you may select to convert attachments or allow special characters, if applicable. ONLY allow special characters if permissible via sponsor guidance.
Click OK. The process will run, and the window will close once its complete. The application will now be in “Valid for Submission State”.
The application is now in a view only status. The blue button reads “View Grant Application” instead of “Edit Grant Application.”
Notice that you may also reopen the application for editing using the “Reopen for Edit” activity on the left side of the page.
The submission pre-check activity is optional but can be run to ensure the SF424 data submitted is formatted correctly for electronic submission.
Click the Submission Pre-Check activity on the SF424 workspace.
A new window will open and provide a message letting you know if the xml generated is valid for submission.
Please notify your GCA Specialist you are ready for submission and that the proposal has been Validated for Submission.
Once in a Valid for Submission State, the GCA Specialist will submit it to Grants.gov within GRAMS. This section outlines what the next steps are following validating the application for submission.
Once the SF424 is in a “Valid for Submission” state, the GCA Specialist will submit the application to Grants.gov.
They will update the funding proposal status to Final Review Status and the Funding Proposal will change to “Pending Submission to Sponsor” which locks the funding proposal from further edits. While in “Pending Submission to Sponsor” status, they will submit the application to Grants.Gov. The GCA Specialist will typically leave the proposal in “Final SPO Review” state until the S2S submission has been accepted and finalized (for instance in eRA Commons). After successful submission is confirmed, the funding proposal will be in “Pending Sponsor Review” State.
When the GCA submits to Grants.Gov, Grants.Gov receives the application and internally process it. It will either be Rejected with errors or be sent on to the federal sponsor. The application will follow the path below.
The statuses from Grants.gov are sent directly to UNT GCA. The Agency Tracking Number and Grant Tracking Number is transmitted as well.
To view this information, refer to the SF424 workspace or the Funding Proposal SF424 Summary tab.
These pages can be referenced to understand the progress of your application in submission to the sponsor.
Change/Correct or Other Errors:
If a proposal is Rejected with Errors from Grants.gov or you identify that changes are needed to the application after submission, work with your GCA to make the needed changes. Only the GCA can reopen the application, edit, and submit change/corrected applications.