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To submit a new Animal Use Protocol or an amendment, annual review report, or closure request for an existing study to the UNT IACUC, please complete the appropriate form (link to Forms pg) and submit your signed final copy to untiacuc@unt.edu. Only eligible Principal Investigators may make a formal submission.

  • Submissions must be complete to be reviewed.  Please use the help text icons decorative imagethroughout the submission form to ensure you are including all items required by UNT Denton IACUC.
  • New protocols are approved for a maximum of 3 years, and the progress of ongoing studies must be reviewed by the IACUC annually through submission of an Annual Review.  Studies that exceed 3 years must submit a triennial renewal protocol prior to the expiration of previous protocol.  Should there be a lapse between the closure of a study and the approval of a renewal submission, all work must stop and any animals on the study must be transferred to the UNT IACUC Holding Protocol.

Review Process

Submissions will be reviewed in the order they are received.  A pre-review for completeness and compliance will be performed by an IACUC Administrator before the documents will be sent to the committee.  The committee will then review submissions through a process called Designated Review, Full Committee Review, or Veterinary Verification and Consultation. 

Submissions going through the Designated Review process will be sent to all committee members, if members do not request that the submission be reviewed at a full committee meeting, the Chair will assign one or two members to review the submission.  Once reviewers have completed their assessment of the documents, they may approve, request modifications, or request that the protocol be reviewed by the Full Committee process through the IACUC Chair and/or Administrators.

Submissions that are deemed to require Full Committee Review will be sent to all committee members at least 2 weeks prior to a committee meeting.  Investigators may be notified when their submission will be reviewed by Full Committee and are invited to attend the meeting to answer any questions the committee may have.  The committee may vote to approve, deny, table, or request modifications on any proposal.  

Once a submission has been approved, the Principal Investigators will receive an official approval letter signed by the committee chair.