UNT to cancel in-person classes March 16-22.

All instruction to resume March 23.

UNT Corona Virus updates Research Continuity and Mitigation due to COVID-19


UNT | University of North Texas

Search form

Cayuse IRB

Cayuse IRB Access

Cayuse IRB Online Submission System: https://unt.cayuse424.com/rs/irb/

  • The Cayuse link will take you to the UNT Single Sign-On page where you may log in with your EUID login and password.
  • If you cannot log into Cayuse IRB, complete an online access request form: Cayuse Access Form
    • Please use Firefox Browser (if you need assistance installing Firefox, please contact UNT Help Desk at http://www.unt.edu/helpdesk/ or 940-565-2324)

  • After successfully logging in, you will see the following image of the Cayuse IRB Dashboard.


Cayuse IRB Resources and Training

Quick Step Guide:
Quick Step Guide

Step-by-Step Submission Guide:
Step-by-Step Submission Guide

Cayuse IRB Help Files:

Cayuse Technical Support:
If you have technical issues with Cayuse IRB, please send an email request to cayusetechsupport@unt.edu.

Request Training
Individual and group training sessions are available to faculty, staff, students. Please contact our office to schedule training: jillian.byrne-sweeney@unt.edu or 940-369-8374.

Cayuse IRB FAQ

Why can’t I log into Cayuse IRB?

Your name may not be in the Cayuse IRB system. You can submit an online request to be granted access to the Cayuse system. Once IT has received the request, you will be added as a user and grants access to Cayuse IRB. This process can take up to 3 business days.

What is the review timeline?

Generally, we ask that you allow 15 business days for a human subjects protocol review. This time may be longer if full board review is required. Your initial submission, once it is reviewed by the Research Analysts, may be sent back to you for revisions, or it may be sent to the IRB Chair or a committee member for review. Notifications and emails are sent to the PIs, Primary Contacts, and other co-investigators at each review stage, and you can always check the status of your protocol in the Cayuse dashboard.  There can be circumstances that delay the review of pending IRB submissions.  Please note that the IRB will communicate all updates and changes as a Dashboard announcement in the Cayuse IRB system.

Is Cayuse IRB training available?

Cayuse training can be found here. The UNT IRB has a step-by-step submission guide on our website here. Also, we have a quick step guide here.

Does Cayuse IRB work more efficiently in certain browsers?

Yes. We recommend using Firefox.

What do I need to submit in Cayuse IRB?

The Initial Submission is the main application, and then you can attach additional documentation directly to the submission. Sections of the submission form allow researchers to attach or cut/paste Word .docs or .pdf documents. You would need to do this, for example, to attach your supporting documentation, such as Informed Consent documents, surveys, and training completion certificates, to name a few.

How are the pre-Cayuse protocols being handled?

All pending or approved protocols, modifications, and any continuing reviews submitted prior to March 1, 2018 will be processed using the former procedures (i.e. emailing Word documents).

Are templates still available to use for supporting documentation such as Informed Consent Templates?

Yes. They are available on our website here.

How are we notified when something needs to be done or the study proceeds through the system?

You will receive notifications generated automatically by Cayuse IRB and will be sent to the PI, the primary contact, and each member of the research team listed under Find People at EACH stage of the review process.

How does Cayuse IRB work if I, as the PI, collaborate with a researcher from another institute- do they have access and do I type in their name as a member of the research team?

External personnel will not have access to our Cayuse IRB. You can list them as unaffiliated key personnel in the appropriate section on the initial submission.

Can Student Investigators (Ph.D., graduate students, etc.) “certify” and/or submit the study and initial submission through Cayuse?

The Student investigator can submit the documentation in Cayuse IRB. However, the initial submission, changes, and any future activity on the study will all have to be certified by the lead PI, or in this case normally the student’s faculty advisor.

What happens when no action is taken by the PI?

Normally if a submission has been sent to the PI for certification, no further editing can occur. In addition, it cannot go forward with screening or review with ORIC, or assignment to the IRB for review, until it has been certified.

How does a person “unlock” a submission- referring to the editing process by Co-PIs who cannot certify?

Once a submission has been forwarded to the next stage of review, it cannot be “unlocked” or edited. Researchers can contact the Office of Research Integrity and Compliance by email and ask that the submission be returned back.

How do I find out the status of the proposal review?

In the Cayuse IRB dashboard, the status of your study can be found under the Submissions icon on the left side menu. You can click on the specific submission for more details.

  • In-Draft: The submission has not been completed and/or submitted for PI approval.
  • Awaiting Approval: The submission is awaiting PI review or certification.
  • Pre-Review: The submission is the Research Compliance Analyst for pre-review.
  • Under Review: The submission has been sent to the IRB reviewer.

How do I delete a submission on an approved study?

There is a point at which researchers can delete an initial submission, a modification, a renewal request, or a closure request. Deleting a submission means it has been completely wiped from the system and is irretrievable. The system allows the user to delete these submissions if they have not been sent for the next level in the review process. Once an action has been performed at the next review level, the submission cannot be deleted.

How long will the research study be available in the Cayuse IRB system after it has been closed?

It will be available for three years after closure/expiration per the UNT Records retention schedule and 45 CFR 46.115(b).

What are incident reports?

Incident reports relate to issues of non-compliance, adverse events, and unanticipated problems with the study. The incident report is designed to allow researchers to self-report these types of issues. Persons wishing to remain anonymous can still report concerns directly to the ORIC.